The present paper deals with the extension of AUSMPW+ scheme into two-fluid model for multiphase flow. AUSMPW+ scheme is the improvement of a single-phase AUSM+ scheme by designing pressure-based weighting functions to prevent oscillations near a wall and shock instability after a strong shock. Recently, Kitamura and Liou assessed a family of AUSM-type schemes with two-fluid model governing equations [K. Kitamura and M.-S. Liou, Comparative study of AUSM-Family schemes in compressible multi-phase flow simulations, ICCFD7-3702 (2012)]. It was observed that the direct application of the single-phase AUSMPW+ did not provide satisfactory results for most of numerical test cases, which motivates the current study. It turns out that, by designing pressure-based weighting functions, which play a key role in controlling numerical diffusion for two-fluid model, problems reported in can be overcome. Various numerical experiments validate the proposed modification of AUSMPW+ scheme is accurate and robust to solve multiphase flow within the framework of two-fluid model.